Research

RESEARCH LINES

• Surveillance of priority infectious diseases in older adults: influenza, SARS-CoV-2, RSV, hMPV, herpes zoster, pneumococcus, meningitis, sepsis, and hospital-acquired infections.

• Immunogenicity, vaccine effectiveness, and waning immunity in frail and long-lived older adults.

• Clinical frailty, immunosenescence, and infectious risk biomarkers.

• Big data, machine learning, and population cohorts applied to intelligent health surveillance in older adults.

• Operational and translational studies on implementing vaccination strategies adapted to older adults in Brazil and Latin America.

• Integrated outbreak surveillance and response models focusing on long-term care institutions, primary care, and hospitals.
  
  

STRATEGIC OBJECTIVES

• Monitor epidemiological trends and patterns of respiratory, bacterial, and viral infections in older adults, with special attention to seasonality, emerging variants, and frailty-related vulnerability.

• Evaluate vaccine effectiveness and durability across different geriatric profiles, considering comorbidities, immunosuppressive treatments, inflammation markers, and nutritional status.

• Develop predictive models and risk panels to guide personalized vaccination strategies, especially for institutionalized or socially vulnerable elders.

• Integrate infectious disease surveillance with demographic data to optimize resource allocation, vaccination campaigns, and impact monitoring.

• Strengthen human resource training via courses, workshops, and academic projects intersecting aging, infection, and vaccination.

• Establish collaborative networks with research centers, public institutions, and international organizations focused on elderly health and immunization.